VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Structural and functional changes in myosin from rat skeletal muscles during postmortem autolysis

   
Nikitina Z.K., Rebrov L.B.
PubMed Id: 2977014
Year: 1988  Volume: 34  Issue: 6  Pages: 76-81
Structure and enzymatic properties of myosin were studied in rat skeletal muscles during various periods of postmortal autolysis. Ca2+-ATPase activity of the protein was decreased within 3 hrs after death. At the same time, the structure of myosin, as shown by gel filtration in 8 M urea and disc electrophoresis in SDS polyacrylamide gel, was maintained. The phenomenon of "substrate inhibition" exhibited both native myosin and the protein isolated from the autolyzed muscle tissue. Enzymatic activity of myosin was markedly decreased within 12 hrs and 24 hrs after death. Degradation of the protein heavy chains was also observed.
Download PDF:  
Citation:

Nikitina, Z. K., Rebrov, L. B. (1988). Structural and functional changes in myosin from rat skeletal muscles during postmortem autolysis. Voprosy Meditsinskoi Khimii, 34(6), 76-81.
References
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
 1986 (vol 32)
 1985 (vol 31)
◄        ►