VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The use of a tripeptide chromogenic substrate for simultaneous determination of 4 indices of kallikrein-kinin system

   
Dotsenko V.L., Iarovaia G.A., Neshkova E.A.
PubMed Id: 2741408
Year: 1989  Volume: 35  Issue: 2  Pages: 128-133
Evaluation of the kallikrein-kinine system activity in blood plasma is of importance due to participation of the components of this system in regulation of blood plasma proteolysis. Using D-Pro-Phe-Arg-pNA as a substrate, a procedure for simultaneous estimation of four patterns of the kallikrein-kinine system activity was developed: I. maintenance of contact phase, 2. content of prekallikrein (1.49 un/ml in normal state), 3. activity of kallikrein (0.104 un/ml), 4. antikallikrein potential (0.700 IU/ml).
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Dotsenko, V. L., Iarovaia, G. A., Neshkova, E. A. (1989). The use of a tripeptide chromogenic substrate for simultaneous determination of 4 indices of kallikrein-kinin system. Voprosy Meditsinskoi Khimii, 35(2), 128-133.
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