VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Molecular aspects of the mechanism of anti-oxidant activity of vitamin E: features of the action of alpha- and gammalphalpha-tocopherol

   
Aĭdarkhanov B.B., Lokshina E.A., Lenskaia E.G.
PubMed Id: 2672579
Year: 1989  Volume: 35  Issue: 3  Pages: 2-9
Current data on mechanisms of vitamin E action are reviewed with the specific reference to the antioxidant theory. Experimental data relevant to this theory on alpha- and gamma-tocopherols reactions in biological and nonbiological systems are considered. Distinctly lower biological activity of gamma-tocopherol, as compared with that of alpha-tocopherol, was shown not to depend only on dissimilar antiradical properties of these two homologues. Tocopherol-binding proteins, exhibiting high affinity only to alpha-tocopherol, appear to be responsible for realization of the biologically important reactions.
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Aĭdarkhanov, B. B., Lokshina, E. A., Lenskaia, E. G. (1989). Molecular aspects of the mechanism of anti-oxidant activity of vitamin E: features of the action of alpha- and gammalphalpha-tocopherol. Voprosy Meditsinskoi Khimii, 35(3), 2-9.
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