VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Low density lipoprotein distribution by flotation characteristics in normal conditions and in dyslipoproteinemias

   
Medvedeva N.V., Morozkin A.D., Goroshkova I.N., Ruuge E.K., Shcherbakova I.A., Perova N.V., Lyakishev A.A.
PubMed Id: 2773382
Year: 1989  Volume: 35  Issue: 3  Pages: 36-41
Distribution of low density (LDL; density range of 1.006-1.063), using the LDL flotation velocity in ultracentrifugation as a criterion, was studied in 4 groups of patients with coronary atherosclerosis (31 patients was examined, 24 of which were with angiographically confirmed coronary atherosclerosis): control group, patients with ischemic heart disease-with normal level of blood plasma lipids, with increased content of triglycerides and with decreased content of LDL cholesterol. The ratio of LDL particles with high hydration density was elevated in the LDL spectrum of all the patients examined. At the same time, each group of patients examined exhibited specific alterations in the LDL distribution spectra.
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Medvedeva, N. V., Morozkin, A. D., Goroshkova, I. N., Ruuge, E. K., Shcherbakova, I. A., Perova, N. V., Lyakishev, A. A. (1989). Low density lipoprotein distribution by flotation characteristics in normal conditions and in dyslipoproteinemias. Voprosy Meditsinskoi Khimii, 35(3), 36-41.
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