VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Properties of monoamine oxidase in the brain of mongolian gerbils during cerebral ischemia

   
Goroshinskaia I.A., Stoianovich T.T., Michich D.V., Mrshulia B.B.
PubMed Id: 2617926
Year: 1989  Volume: 35  Issue: 5  Pages: 112-115
Properties of monoamine oxidase (MAO) were investigated in mongolian gerbils brain mitochondria isolated from cerebral cortex, striatum and hippocampus during cerebral ischemia. 5 min of ischemia caused inhibition of MAO activity (kynuramine as a substrate), alterations in substrate specificity and in kinetic curves form deflexion from hyperbolic type in all the brain structures investigated. Alterations in properties of MAO were observed in hippocampus already after I min of ischemia.
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Goroshinskaia, I. A., Stoianovich, T. T., Michich, D. V., Mrshulia, B. B. (1989). Properties of monoamine oxidase in the brain of mongolian gerbils during cerebral ischemia. Voprosy Meditsinskoi Khimii, 35(5), 112-115.
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