VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Phospholipid-glycerides, cross-resistance of erythrocytes, malonic dialdehyde level and alphalphalpha-tocopherol levels in the plasma and erythrocytes of rats with alloxan diabetes before and after combined antioxidant therapy

   
Karagezian K.G., Gevorkian D.M.
PubMed Id: 2617931
Year: 1989  Volume: 35  Issue: 5  Pages: 27-30
Quantitative and qualitative alterations in content of phospholipids were studied in erythrocytes of rats with alloxan diabetes: rate of lipid peroxidation and content of L-tocopherol were estimated in blood plasma before and after the antioxidant therapy. Patterns of lipid metabolism were normalized after the course of treatment involving simultaneous administration of L-tocopherol and ascorbic acid within 10-15 days. The antioxidants used decreased the rate of lipid peroxidation in erythrocyte membranes and stimulated biosynthesis of phospholipids de novo. Role of antioxidants in phospholipid metabolism is discussed.
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Karagezian, K. G., Gevorkian, D. M. (1989). Phospholipid-glycerides, cross-resistance of erythrocytes, malonic dialdehyde level and alphalphalpha-tocopherol levels in the plasma and erythrocytes of rats with alloxan diabetes before and after combined antioxidant therapy. Voprosy Meditsinskoi Khimii, 35(5), 27-30.
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