VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The effect of tetracycline and silibore on lipid peroxidation in the liver od rats of various age

   
Lemeshko V.V., Dorkina E.G., Nikitchenko Yu.V., Vasilenko Yu.K.
PubMed Id: 2617936
Year: 1989  Volume: 35  Issue: 5  Pages: 49-54
As shown by accumulation of malonic dialdehyde and chemiluminescence rate monitoring tetracycline activated both NADPH- and ascorbate-dependent lipid peroxidation in liver tissue of 1, 3, 12 and 24 months old rats. The most distinct induction of lipid peroxidation was observed in old animals, which appears to occur due to a decrease in efficiency of NADPH-GSH-dependent enzymatic antioxidant system. Silibore prevented the stimulating effect of tetracycline on enzymatic and nonenzymatic lipid peroxidation, being apparently involved in hepatoprotective effect.
Download PDF:
Citation:

Lemeshko, V. V., Dorkina, E. G., Nikitchenko, Yu. V., Vasilenko, Yu. K. (1989). The effect of tetracycline and silibore on lipid peroxidation in the liver od rats of various age. Voprosy meditsinskoi khimii, 35(5), 49-54.
References
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
 1986 (vol 32)
 1985 (vol 31)