VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Isolation and various physico-chemical properties of diabetogenic factor from the blood of patients with diabetes

   
Kudriashov B.A., Liapina L.A., Azieva L.D.
PubMed Id: 2629241
Year: 1989  Volume: 35  Issue: 6  Pages: 63-66
A preparation of diabetogenic factor was purified 660-fold using affinity chromatography on heparin-Sepharose. Homogeneity of the preparation and its molecular mass (about 60 kDa) were evaluated in, polyacrylamide gel electrophoresis. The fraction with high affinity to heparin exhibited the highest biological activity and was eluted by a solution with high ionic strength (1.5 M NaCl). Biological activity of the diabetogenic factor preparation correlated with its concentration in blood plasma in vitro.
Download PDF:
Citation:

Kudriashov, B. A., Liapina, L. A., Azieva, L. D. (1989). Isolation and various physico-chemical properties of diabetogenic factor from the blood of patients with diabetes. Voprosy meditsinskoi khimii, 35(6), 63-66.
References
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
 1986 (vol 32)
 1985 (vol 31)