VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Mitochondrial oxidation in the liver during visceral-ischemic shock

   
Levin G.S., Tremasova G.Ya., Gubaev S.A.
PubMed Id: 2238530
Year: 1990  Volume: 36  Issue: 4  Pages: 34-37
Distinct decrease in respiratory and phosphorylating functions of liver mitochondria was found under conditions of visceral-ischemic shock induced in rabbits after 2 hrs occlusion of superior mesenteric artery and the subsequent step-by-step revascularization. Endogenous intoxication was mainly responsible for inhibition of electron transport through respiratory chain. Impairment of mitochondrial oxidation is one of important factors related to development of the shock "irreversible" phase.
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Levin G.S., Tremasova G.Ya., Gubaev S.A. (1990) Voprosy meditsinskoi khimii, 36(4), 34-37.
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