VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Various characteristics of protein-synthesizing apparatus of the myocardium during total ischemia

   
Maskoliunas R.K., Lekis A.V., Kovalenko M.I., El'skaia A.V., Lukoshiavichius L.Iu.
PubMed Id: 2238536
Year: 1990  Volume: 36  Issue: 4  Pages: 7-10
A decrease in the rate of protein synthesis as well as an increase in the synthesis time of "medium-size" polypeptide chain were detected in total rabbit myocardium ischemia, which were evaluated using rabbit myocardium cell-free protein-synthesizing systems. The decrease in the synthesis rate of total myocardial proteins was shown to depend on the state of ribosomes function. Redistribution in the pools of membrane-bound and free ribosomes as well as a decrease of polyribosomes amount in total pool of myocardial ribosomes were observed under conditions of total myocardial ischemia.
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Maskoliunas R.K., Lekis A.V., Kovalenko M.I., El'skaia A.V., Lukoshiavichius L.Iu. (1990) Voprosy meditsinskoi khimii, 36(4), 7-10.
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