VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Antioxidative properties of glycyrrhyzic acid salts and their effect on the liver monooxygenase system

   
Abdugafurova M.A., Li V.S., Sherstnev M.P., Atanaev T.B., Isamukhamedov A.Sh., Bachmanova G.I.
PubMed Id: 2251786
Year: 1990  Volume: 36  Issue: 5  Pages: 29-31
Antioxidative activity of potassium- and sodium glycyrrhizins was detected by means of chemoluminescence procedure. As shown by the spectral studies the glycyrrhizin salts formed complex of the I type with cytochrome P-450 from rat liver microsomes, inhibited inactivation of isolated cytochrome P-450LM2 and induced hemoprotein formation after administration into rats. The preparations of glycyrrhizic acid appear to be useful for treatment of toxic impairment of liver tissue.
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Abdugafurova, M. A., Li, V. S., Sherstnev, M. P., Atanaev, T. B., Isamukhamedov, A. Sh., Bachmanova, G. I. (1990). Antioxidative properties of glycyrrhyzic acid salts and their effect on the liver monooxygenase system. Voprosy Meditsinskoi Khimii, 36(5), 29-31.
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