VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Hetero-oligoproteins containing pancreatic ribonuclease--enzyme conjugates of prolonged action

   
Goriacheva L.K., Medvedev M.L., Samsonov G.V., Ponomareva R.B.
PubMed Id: 2251790
Year: 1990  Volume: 36  Issue: 5  Pages: 4-6
Conjugates containing blood serum albumin and pancreatic ribonuclease, produced by means of polycondensation reaction, exhibited higher half-life in rabbit circulation as compared with non-modified enzyme. Presence of the protein-carrier contributed to elevation of the ribonuclease therapeutic efficiency and enabled to decrease the quantity of injections.
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Goriacheva, L. K., Medvedev, M. L., Samsonov, G. V., Ponomareva, R. B. (1990). Hetero-oligoproteins containing pancreatic ribonuclease--enzyme conjugates of prolonged action. Voprosy Meditsinskoi Khimii, 36(5), 4-6.
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