VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

A mathematical model of apolipoprotein B metabolism in human blood plasma

   
Iarovaia E.B., Metel'skaia V.A., Perova N.V.
PubMed Id: 1858349
Year: 1991  Volume: 37  Issue: 1  Pages: 8-12
Mathematical model was developed for transport of apo B in blood plasma, which allowed to estimate constants of metabolism of lipoproteins containing apo B, considering the alterations of apo B concentration in circulation followed by immuno- or hemosorption. Some cases were detected where stimulating effect of these procedures on the rate of apo B entering into circulation was found as well as definite ratios were shown between the constants using the parameters of alterations in apo B concentration after elimination of lipoproteins containing apo B from blood plasma. Existence of cases was predicted where fluctuations in apo B concentration attenuated after immuno- and hemosorption which were difficult to find in experiments.
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Iarovaia, E. B., Metel'skaia, V. A., Perova, N. V. (1991). A mathematical model of apolipoprotein B metabolism in human blood plasma. Voprosy Meditsinskoi Khimii, 37(1), 8-12.
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