VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Changes in the fatty acid composition of myocardial phospholipids after hypothermic ischemia

   
Boiarinov G.A., Andreeva N.N.
PubMed Id: 1949689
Year: 1991  Volume: 37  Issue: 3  Pages: 54-56
Index of phospholipids saturation was increased in myocardium within 90 min reperfusion after hypothermic (8-12 degrees) ischemia. Content of oleic, linoleic and arachidonic acids was decreased in all the phospholipid fractions studied thus suggesting that phospholipase mechanism was involved in cardiomyocyte membranes impairment. However, mechanisms of adaptation-protective reactions were maintained as synthesis of prostaglandins from these fatty acids was possible and amount of polyenic acids (eicosapentaenic, decasatetraenoic acids) was increased in some phospholipids. Data of literature corroborated this suggestion.
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Boiarinov G.A., Andreeva N.N. (1991) Voprosy meditsinskoi khimii, 37(3), 54-56.
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