VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Regional activity of enkephalin- and angiotensin II-forming peptidases in the rat brain and other peripheral tissues with different craving for ethanol

   
Gomazkov O.A., Panfilov A.D., Rostovtsev A.P., Komissarova N.V., Fomin V.V., Grigor'iants O.O.
PubMed Id: 1661050
Year: 1991  Volume: 37  Issue: 4  Pages: 33-37
Activities of enkephalin- and angiotensin II-forming enzymes (carboxypeptidase H and angiotensin-converting enzyme, ACE) were changed in different brain regions and peripheral tissues of rats with various alcohol motivation. The carboxypeptidase H activity was elevated in midbrain, striatum, hypophysis and adrenal glands, while the ACE activity was increased in hypophysis and striatum. The ACE activity was decreased two-fold in thalamo-hypothalamic region of ethanol-preferring rats.
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Gomazkov, O. A., Panfilov, A. D., Rostovtsev, A. P., Komissarova, N. V., Fomin, V. V., Grigor'iants, O. O. (1991). Regional activity of enkephalin- and angiotensin II-forming peptidases in the rat brain and other peripheral tissues with different craving for ethanol. Voprosy Meditsinskoi Khimii, 37(4), 33-37.
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