VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Rat liver mitochondrial DNA treated with 1,2-dimethylhydrazine

   
Fedorov S.N., Balanski R.M., Novikov L.B., Levanova G.I., Likhachev A.Ya., Anisimov V.N., Khanson K.P.
PubMed Id: 1812622
Year: 1991  Volume: 37  Issue: 6  Pages: 82-84
Primary structure of 5'-end 16S RNA gene of mitochondrial DNA (mDNA) isolated from rat liver tissue within 20 hrs after treatment with 1,2-dimethyl hydrazine, was analyzed. The preparations studied did not contain mutations induced by the drug. The region of mDNA analyzed appears not to be a preferential target for mutagenic effect of 1,2-dimethyl hydrazine unber these experimental conditions.
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Fedorov, S. N., Balanski, R. M., Novikov, L. B., Levanova, G. I., Likhachev, A. Ya., Anisimov, V. N., Khanson, K. P. (1991). Rat liver mitochondrial DNA treated with 1,2-dimethylhydrazine. Voprosy Meditsinskoi Khimii, 37(6), 82-84.
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