Primary structure of 5'-end 16S RNA gene of mitochondrial DNA (mDNA) isolated from rat liver tissue within 20 hrs after treatment with 1,2-dimethyl hydrazine, was analyzed. The preparations studied did not contain mutations induced by the drug. The region of mDNA analyzed appears not to be a preferential target for mutagenic effect of 1,2-dimethyl hydrazine unber these experimental conditions.
Fedorov S.N. et al. Rat liver mitochondrial DNA treated with 1,2-dimethylhydrazine // Voprosy meditsinskoi khimii. - 1991. - V. 37. -N 6. - P. 82-84.
Fedorov S.N. et al., "Rat liver mitochondrial DNA treated with 1,2-dimethylhydrazine." Voprosy meditsinskoi khimii 37.6 (1991): 82-84.
Fedorov, S. N., Balanski, R. M., Novikov, L. B., Levanova, G. I., Likhachev, A. Ya., Anisimov, V. N., Khanson, K. P. (1991). Rat liver mitochondrial DNA treated with 1,2-dimethylhydrazine. Voprosy meditsinskoi khimii, 37(6), 82-84.