VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Degradation of endo- and exogenous albumin in normal and starved rats

   
Mal'tsev G.Yu., Vasil'ev A.V.
PubMed Id: 1492384
Year: 1992  Volume: 38  Issue: 5  Pages: 10-12
A rate of degradation of homologous exogenous 14C-albumin proved to be higher 3-fold as compared with that of endogenous 14C-albumin, while the albuminolysis rate was additionally increased in starvation. Evaluation of 14C- and 3H-labels demonstrated that the protein hydrolysis occurred mainly in liver tissue, kidney and intestinal membrane and its rate was elevated in starvation. Dissimilar secretion of exo- and endogenous albumins into small intestine lumen was detected. Removal of albumins was found to depend on augmentation in the proteolytic potential and on reconstructive activity of secondary lysosomes
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Mal'tsev, G. Yu., Vasil'ev, A. V. (1992). Degradation of endo- and exogenous albumin in normal and starved rats. Voprosy Meditsinskoi Khimii, 38(5), 10-12.
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