VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Antimutagenic properties of substances containing beta-carotene

   
Shliankevich M.A., Drize O.B., Khabibulina V.M., Sergeev A.V., Privalova E.G., Nikitiuk V.G.
PubMed Id: 1298121
Year: 1992  Volume: 38  Issue: 6  Pages: 23-25
Two carotene-containing drugs (natural and artificial) were shown to decrease the rate of chromosomal aberrations, induced by cyclophosphane, in bone marrow cells of mice, daily ration of which contained 10-20 mg/kg of beta-carotene within 1-3 weeks. The rate of chromosomal aberrations induced was decreased 1.5-2-fold in various experiments. Artificial beta-carotene exhibited aftereffect within at least 3 days, while its protective effect was decreased about by 20% within 7 days after administration.
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Shliankevich, M. A., Drize, O. B., Khabibulina, V. M., Sergeev, A. V., Privalova, E. G., Nikitiuk, V. G. (1992). Antimutagenic properties of substances containing beta-carotene. Voprosy Meditsinskoi Khimii, 38(6), 23-25.
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