VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Level of fructose-2,6-bisphosphate and activity of fructose-1,6-bisphosphatase in hepatocyte suspensions in streptozotocin diabetes

   
Golubev M.A., Markova M.S., Stvolinskaia N.S.
PubMed Id: 8303862
Year: 1993  Volume: 39  Issue: 6  Pages: 13-15
Content of fructose-2,6-bisphosphate was drastically decreased (about 5-fold) in hepatocyte suspension obtained from rats with streptozotocin-induced diabetes, as compared with that of control animals. At the same time, activity of fructose-1,6-bisphosphatase was increased 2-fold in these hepatocytes. Incubation mixture of the hepatocytes from the diabetes impaired animals contained only low amounts of lactate.
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Golubev, M. A., Markova, M. S., Stvolinskaia, N. S. (1993). Level of fructose-2,6-bisphosphate and activity of fructose-1,6-bisphosphatase in hepatocyte suspensions in streptozotocin diabetes. Voprosy meditsinskoi khimii, 39(6), 13-15.
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