VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Tuftsin-like peptides from a C-reactive protein molecule as regulators of lymphocyte proliferation

   
Polevshchikov A.V., Nazarov P.G.
PubMed Id: 8122411
Year: 1994  Volume: 40  Issue: 1  Pages: 4-7
Influence of synthetic peptides from human C-reactive protein (CRP) on proliferation of intact and mitogen stimulated peripheral blood lymphocytes was studied. Effect of the tetra-peptides from CRP was similar to that of tuftsin Thr-Lys-Pro-Arg. All the peptides studied did not increase the 3H-thymidine incorporation into the resting lymphocytes but accelerated it after mitogen stimulation. The peptides efficiency depended on T- or B-specificity of mitogens.
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Polevshchikov A.V., Nazarov P.G. (1994) Voprosy meditsinskoi khimii, 40(1), 4-7.
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