VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Preparation of physiologically active polymethylmethacrylate on lanthanoid silylamides

   
Zhil'tsov S.F., Shustov S.B., Bochkarev L.N., Malyshev E.S., Sedova T.E.
PubMed Id: 8160433
Year: 1994  Volume: 40  Issue: 2  Pages: 52-54
Catalytic activity of silylamide derivatives of three-valent lanthanoids [(Me3Si)2N]3Ln (where Me-CH3; Ln-Pr, Sm, Eu, Gd, Tb, Er, Yb) was studied under conditions of low temperature polymerization of methacrylate. The reaction involved an anion-dependent mechanism and was accompanied by formation of block polymer. The physiological activity of the polymethacrylate produced was manifested as stimulation of the growth rate in bone tissue after its impairments. The organo-element fragment introduced into the polymer was responsible for this kind of activity.
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Zhil'tsov, S. F., Shustov, S. B., Bochkarev, L. N., Malyshev, E. S., Sedova, T. E. (1994). Preparation of physiologically active polymethylmethacrylate on lanthanoid silylamides. Voprosy Meditsinskoi Khimii, 40(2), 52-54.
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