VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Metabolism of neutral lipids in hemopoietic organs and in the liver of mice with alloxan diabetes

   
Kozlov I.A., Saprykina E.V., Baĭkov A.N., Novitskiĭ V.V.
PubMed Id: 7839658
Year: 1994  Volume: 40  Issue: 5  Pages: 12-15
The metabolism of neutral lipids (free and ester-bound cholesterols, mono-, di- and triacylglycerides) was greatly impaired in liver, spleen, thymus tissues and ileocecal lymph nodes of BALB/c mice with subacute alloxan diabetes (content of sugar in blood was no less than 14 mmol/l) as shown by 3H-acetate and 14C-palmitate incorporation into the corresponding lipid fractions. The rate of neutral lipid turnover was specifically decreased in all the tissues studied. However, a considerable accumulation of these lipid fractions was found in thymus tissue. Incorporation of labelled palmitate into triacylglycerides was increased in the spleen but without obesity of the organ
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Kozlov, I. A., Saprykina, E. V., Baĭkov, A. N., Novitskiĭ, V. V. (1994). Metabolism of neutral lipids in hemopoietic organs and in the liver of mice with alloxan diabetes. Voprosy Meditsinskoi Khimii, 40(5), 12-15.
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