Analysis of many-year people vitaminization with thiamine showed that middle values of the TDP-effect were not always decreased down to the level of < or = 1.15. The TDP-effect not exceeding 1.25 value should be recommended as a criterion of normal vitamin B1 consumption as followed from mathematical analysis of the correlation between excretion of thiamine with urine and the TDP-effect value as well as from plotting and mathematical interpretation of the variation curves involving distribution of the TDP-effect value among people with additional vitaminization. The literature available data equal to 1.15 appears to exhibit the optimum rate of the vitamin consumption. Excretion of thiamine with urine more than 12 mg/h should be also considered as a normal consumption of vitamin B1 in children of 12 years old and older and in adults. The criteria of vitamin B2 consumption in children of this age were similar to corresponding patterns of adults: minimal concentration of riboflavin in blood plasma was about 6 ng/ml and its excretion with urine--about 14 mg/h.
Kodentsova V.M. et al. Refining criteria for providing adults and 12-14 year old children with vitamins B1 and B2 // Voprosy meditsinskoi khimii. - 1994. - V. 40. -N 6. - P. 45-48.
Kodentsova V.M. et al., "Refining criteria for providing adults and 12-14 year old children with vitamins B1 and B2." Voprosy meditsinskoi khimii 40.6 (1994): 45-48.
Kodentsova, V. M., Kharitonchik, L. A., Vrzhesinskaia, O. A., Abramova, E. I., Shumilova, S. L., Spirichev, V. B. (1994). Refining criteria for providing adults and 12-14 year old children with vitamins B1 and B2. Voprosy meditsinskoi khimii, 40(6), 45-48.