VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Bioavailability and pharmacodynamics of various forms of synthetic beta-carotene in volunteers

   
Iakushina L.M., Malakhova E.A., Shkarina T.N., Poznanskaia A.A., Spirichev V.B.
Section:
PubMed Id: 8571585
Year: 1995  Volume: 41  Issue: 4  Pages: 36-41
The biological availability of artificial beta-carotene as a water-soluble versus oily formulation based on cyclodextrin (Cyclocar tablets) was studied on volunteers given a single dose of 25 mg. The concentrations of beta-carotene and major carotenoids were measured in the blood serum during the experiment by high performance liquid chromatography. The maximum content of beta-carotene in the serum was attained 24-30 and 30-48 hrs after oily formulations and Cyclocar and were 48.0 +/- 7.7 and 28.1 +/- 3.6 mg/dl, respectively. The rate of beta-carotene utilization from Cyclocar was 2.2 times less than that from the oil paste. Besides, beta-carotene absorbed from these oily drugs retained in the blood serum for longer period than that form Cyclocar
Download PDF:  
Citation:

Iakushina, L. M., Malakhova, E. A., Shkarina, T. N., Poznanskaia, A. A., Spirichev, V. B. (1995). Bioavailability and pharmacodynamics of various forms of synthetic beta-carotene in volunteers. Voprosy Meditsinskoi Khimii, 41(4), 36-41.
References
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
 1986 (vol 32)
 1985 (vol 31)
◄        ►