VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Features of B group vitamin metabolism and criteria for providing them to children suffering from celiac disease

   
Kodentsova V.M., Uspenskaia I.D., Vrzhesinskaia O.A., Kharitonchik L.A., Sokol'nikov A.A., Iakushina L.M., Makarova I.B., Spirichev V.B.
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PubMed Id: 8571586
Year: 1995  Volume: 41  Issue: 4  Pages: 41-45
The investigation into the relationship between the concentration of vitamins B, the blood activity of vitamin B-dependent enzymes and the urinary excretion of their metabolites in 14 children of both sexes whose age was 4.5-10 years and who suffered from celiac disease has characterized their metabolic features. The criteria for vitamin B1 provision of these children differ from those in healthy children of the same age: the normal value of TDP effects is achieved with higher thiamine excretion which is more than 12 micrograms/h. Apparently, the plasma concentration of riboflavin greater than 14 ng/ml and its urinary excretion 6 micrograms/h should be taken as a criterion for normal vitamin B2 provision. Though due to a small proportion of the examined children, criteria for vitamin B6 and nicotinic acid could not be defined. The excretion of 4-pyridoxylic acid in the whole concentration ranges of pyridoxylic coenzymes in the plasma of sick children was essentially lower than that in healthy persons.
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Kodentsova V.M., Uspenskaia I.D., Vrzhesinskaia O.A., Kharitonchik L.A., Sokol'nikov A.A., Iakushina L.M., Makarova I.B., Spirichev V.B. (1995) Voprosy meditsinskoi khimii, 41(4), 41-45.
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