VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Possibility of the use of erythrocyte antioxidant enzymes as indicators characterising the development of disease in patients with hemoblastoses

   
Kumerova A.O., Petukhov V.I., Shkesters A.P., Silova A.A., Letse A.G.
PubMed Id: 9148601
Year: 1996  Volume: 42  Issue: 2  Pages: 144-147
Blood and erythrocytes of 50 healthy volunteers and 105 patients with different forms of hemoblastoses were investigated. 54 patients had acute phase, 51 patients--remission stage of disease. Essential differences in the activity of antioxidant enzymes (SOD, CAT, GSH-Px) were detected and compared with content of MDA and degree of anaemia. Acute phase had more significantly alteration of antioxidant defence: diverse changes of the activity of SOD and CAT, significantly inhibition of GSH-Px, the high level of MDA and increased degree of anaemia.
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Kumerova, A. O., Petukhov, V. I., Shkesters, A. P., Silova, A. A., Letse, A. G. (1996). Possibility of the use of erythrocyte antioxidant enzymes as indicators characterising the development of disease in patients with hemoblastoses. Voprosy meditsinskoi khimii, 42(2), 144-147.
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