The hemoprotein self-inactivation is accompanied by oxidation of all-groups, carbonyl group formation, changes in aggregate state and apoenzyme polymerization. It is probable that heme loss and oxidative modification of apoenzyme is a important step in regulation of P450 decay in cell
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Zgoda V.G., Karuzina I.I., Nikityuk O.W., Archakov A.I. (1996) Oxidative modification of apoenzyme of cytochrome P450 during its catalytic self-inactivation in the reconstituted monooxifgenase system. Voprosy Meditsinskoi Khimii, 42(3), 203-210.
Zgoda V.G. et al. Oxidative modification of apoenzyme of cytochrome P450 during its catalytic self-inactivation in the reconstituted monooxifgenase system // Voprosy Meditsinskoi Khimii. - 1996. - V. 42. -N 3. - P. 203-210.
Zgoda V.G. et al., "Oxidative modification of apoenzyme of cytochrome P450 during its catalytic self-inactivation in the reconstituted monooxifgenase system." Voprosy Meditsinskoi Khimii 42.3 (1996): 203-210.
Zgoda, V. G., Karuzina, I. I., Nikityuk, O. W., Archakov, A. I. (1996). Oxidative modification of apoenzyme of cytochrome P450 during its catalytic self-inactivation in the reconstituted monooxifgenase system. Voprosy Meditsinskoi Khimii, 42(3), 203-210.
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