VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Experimental study of formaldehyde action on the enzyme activity of rat liver during ontogenesis

   
Astakhova L.F., Mukhambetova L.H., Koganova Z.I., Dolinskaya S.I., Kazachkov V.I., Zhurkov V.S.
Section: Experimental Study
PubMed Id: 9139453
Year: 1996  Volume: 42  Issue: 3  Pages: 217-222
The pregnant rats were treated with formaldehyde (0.5 mg/kg daily per os) during whole period of pregnancy. The activity of cytochrome-c-oxidase, malate dehydrogenase, nucleotidase, glucose-6-phosphatase, beta-glucuronidase, N-acetyl-beta-glucosaminidase, beta-galactosidase, H(+)-ATPase, glutamate dehydrogenase, NAD- and NADP-isocitrate dehydrogenase, fructose-bisphosphate aldolase, glucose-6-phosphate dehydrogenase and content of protein in liver celts of offsprings (newborns, 2 weeks age and 2 months age) were studied. It was shown differences in development enzyme systems of control and experimental animals during ontogenesis.
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Astakhova, L. F., Mukhambetova, L. H., Koganova, Z. I., Dolinskaya, S. I., Kazachkov, V. I., Zhurkov, V. S. (1996). Experimental study of formaldehyde action on the enzyme activity of rat liver during ontogenesis. Voprosy meditsinskoi khimii, 42(3), 217-222.
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