The influence of oral inulin administration on glucose and fructose content in blood, glucose and ketone bodies in urine, and fructose-2,6-diphosphate content in liver was investigated in rats with streptozotocin diabetes. Short-term administration (during 5-6 days) of 0,5% inulin solution caused three-fold increase of blood fructose compared with control, normalisation of blood glucose and disappearance of glucose- and ketoneuria. The level of fructose-2,6-diphosphate in liver increased to the control level. Inulin administration during 12 days caused five-fold increase of blood fructose compares with control, glucose level increased up to the level of uncured diabetes (22 mmol/l), glucose- and ketoneuria appeared. The content of fructose-2,6-diphosphate in the liver decreased to diabetic level.
Guseva D.A., Gorodetsky V.K., Kraevoi S.A., Markova M.S., Tsyganova T.B. (1997) The influence of oral inulin administration on fructose-2, 6-diphosphate level in liver of rats with streptozotocin diabetes. Voprosy Meditsinskoi Khimii, 43(4), 247-255.
Guseva D.A. et al. The influence of oral inulin administration on fructose-2, 6-diphosphate level in liver of rats with streptozotocin diabetes // Voprosy Meditsinskoi Khimii. - 1997. - V. 43. -N 4. - P. 247-255.
Guseva D.A. et al., "The influence of oral inulin administration on fructose-2, 6-diphosphate level in liver of rats with streptozotocin diabetes." Voprosy Meditsinskoi Khimii 43.4 (1997): 247-255.
Guseva, D. A., Gorodetsky, V. K., Kraevoi, S. A., Markova, M. S., Tsyganova, T. B. (1997). The influence of oral inulin administration on fructose-2, 6-diphosphate level in liver of rats with streptozotocin diabetes. Voprosy Meditsinskoi Khimii, 43(4), 247-255.
Golubev M.A., Stvolinskaya N.S., Markova M.S., Beltaeva N.F., Balabolkin M.J., Korovkin B.F.//in: Pathobiochemical aspekts of extreme states. Mir Publisher, M. -1994. -P.68-77. Scholar google search
