VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The influence of bovine serum albumine on the autolytic alterations of the lipid component of rat brain grey and white matters tissue in vitro

   
Gribanov G.A., Golovko M.U.
PubMed Id: 9703623
Year: 1998  Volume: 44  Issue: 3  Pages: 241-247
The influence of cytoprotecting concentrations of bovine serum albumin (BSA) on the autolytic alterations of rat brain white and grey matters in the physiological solution containing was investigated, In the autolysed grey matter exogenous BSA prevents the decomposition of phospholipids and the gaining the free fatty acids up to 1 hr of incubation and increased the content of cholesterol esters at the 4th and 24th hrs of autolysis BSA increased the phospholipids breakdown at the late stages of autolysis (24 hrs). On the contrary, BSA activated the phospholipids break down in the white matter already at the early periods of incubation (10 mins). It also altered the character of cholesterol and esters pendulous interactions on the opposite one, promoting the significant increase of the latters, especially at the 10th min and 4th hr of the autolysis
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Keywords: autolysis, lipid metabolism, grey and white matters of animal brain, albumine
Citation:

Gribanov, G. A., Golovko, M. U. (1998). The influence of bovine serum albumine on the autolytic alterations of the lipid component of rat brain grey and white matters tissue in vitro. Voprosy meditsinskoi khimii, 44(3), 241-247.
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