Proteolytical preparation moricrasa was isolated from hepatopancreas of Paralithodes camtshatic. Moricrasa and its fractions were used for lysis of cicatricial tissue under in vitro conditions. It was found that moricrasa in concentrations 0.5 mg/ml and 2 mg/ml lysed the cicatrix during 72 and 14-16 hours, respectively. The fraction consisted of collagenolytic proteinase PC and trypsin revealed maximal activity of fraction of moricrasa was absent.
Liutova L.V., Karabasova M.A., Andreenko G.V., Rudenskaya G.N., Isaev V.A., Brusov A.B. (1998) The effect of proteolytic preparation moricrasa on cicatricial tissue studied in vitro. Voprosy Meditsinskoi Khimii, 44(3), 292-295.
Liutova L.V. et al. The effect of proteolytic preparation moricrasa on cicatricial tissue studied in vitro // Voprosy Meditsinskoi Khimii. - 1998. - V. 44. -N 3. - P. 292-295.
Liutova L.V. et al., "The effect of proteolytic preparation moricrasa on cicatricial tissue studied in vitro." Voprosy Meditsinskoi Khimii 44.3 (1998): 292-295.
Liutova, L. V., Karabasova, M. A., Andreenko, G. V., Rudenskaya, G. N., Isaev, V. A., Brusov, A. B. (1998). The effect of proteolytic preparation moricrasa on cicatricial tissue studied in vitro. Voprosy Meditsinskoi Khimii, 44(3), 292-295.
References
Исаев В.А., Руденская Г.Н., Купенко ОТ, Степанов В.М., Попова И.М., Диденко Ю.Т. (1991) Способ получения препарата коллагеназы патент 2008353 от 5 августа Бюлл.изобр.№4, 1994 г. Scholar google search
Климова О.А., Ведищева Ю.В., Стронгин А.Я. (1991) Докл.Акад.Наук СССР, 317 (2), 482-484. Scholar google search
