The system of the endothelin peptides: mechanisms of the cardio-vascular pathologies
Gomazkov O.A. PubMed Id: 10547878
Year: 1999 Volume: 45 Issue : 4 Pages: 290-303 A rapidly growing body of data support the concept of endothelin as a paracrine acting endothelial regulators. The system of endothelin peptides--their chemical structure, physiological activity and role in cardiovascular pathological processes are reviewed. Molecular specificity, isoforms, and physicochemical parameters of the endothelin-converting enzyme (ECE) characterize this novel metalloproteinase as important regulator, that catalyses final step in the biosynthesis of endothelins. The role of the general endothelial system for various cardiovascular pathological states, including congestive heart failure and myocardial infarction, arterial hypertension, atherosclerotic vascular diseases is discussed. Therapeutic approaches with some endothelin receptor antagonists and ECE inhibitors are discussed, and endothelin system therefore represents a likely target for the development for the novel pharmaceutical agents.Download PDF: Keywords: regulatory peptides, endothelin, endothelin-converting enzyme, cardiovascular disorders, theurapeutical approach
Citation:
APA
MLA
BMC standart
GOST
Gomazkov O.A. (1999) The system of the endothelin peptides: mechanisms of the cardio-vascular pathologies. Voprosy Meditsinskoi Khimii, 45 (4), 290-303.
et al. The system of the endothelin peptides: mechanisms of the cardio-vascular pathologies // Voprosy Meditsinskoi Khimii. - 1999. - V. 45. -N 4. - P. 290-303.
et al., "The system of the endothelin peptides: mechanisms of the cardio-vascular pathologies." Voprosy Meditsinskoi Khimii 45.4 (1999): 290-303.
Gomazkov, O. A. (1999). The system of the endothelin peptides: mechanisms of the cardio-vascular pathologies. Voprosy Meditsinskoi Khimii , 45(4), 290-303.
References Show
Yanagasawa M., Kurihara К, Kimura S., Tomobe Y. et al. (1988), Nature, 332, 411-415. Scholar google search Monge J.C. (1998) J Cardiovasc. Pharmacol., 32 (Suppl.2), S36-S42. Scholar google search Antoniucci D., Fitzpatrick L.A. (1996) Endocrinologist, 6(6), 481 -487. Scholar google search Maeda S., Miyauchi Т., Goto K., Matsuda M. (1997) Life Sci., 61(4), 419-425. Scholar google search La M. and Reid J. (1995) Clin. Exp. Pharmacol. Physiol., 22, 315-323. Scholar google search Sarisom C, Hoang V., Turner A. (1995) J. Cardiovasc. Pharmacol., 26, Suppl. 3, S75-S77. Scholar google search Takahashi M., Matsushita Y., lijima Y., Tanzawa K. (1993) J. Biol. Chem., 268, 21394-21398. Scholar google search Xu D., Ernoto N., Giaid A., Slaughter C, Kaw S. et al. (1994) Cell, 78, 473-485. Scholar google search Barnes K., Brown C, Turner A.J. (1998) Hypertension, 31(1), 3-9. Scholar google search Schweizer A., Valdenaire O., Nelbock P., Deuschle U. et al. (1997) Biochem. J., 328(Part3), 871-877. '. Scholar google search Parnot C, Lemoullec J.M., Cousin M.A., Guedin D. et al. (1997) Hypertension, 30(4), 837-844. Scholar google search Russell F., Skepper J.N., Davenport A.P. (1998) Circul. Res., 83(3), 314-321. Scholar google search Naomi S., Iwaoka Т., Disashi Т., Inoue J., Kanesaka Y. et al. (1998) Circulation, 97(3), 234-236. Scholar google search Гомазков О.А. (1998) Биохимия, 63(2), 12-20. Scholar google search Davenport A.P., Kuc R.E., Plumpton C, Mockridge J.M. et al. (1998) Histochem. J., 30(5), 359-374. Scholar google search Hoang M. V., Turner A. (1997) Biochem. J., 327(Part 1), 23-26. Scholar google search Johnson G.D., Stevenson Т., Ahn K.H. (1999) J. Biol. Chem., 274(7), 4053-4058. Scholar google search Subkowski Т., Hillen K, Kroger В., Schmidt M. (1998) J. Immunoassay, 19(2/3), 75-93. Scholar google search Schiffrin E.L., Touyz R.M. (1998) J. Cardiovasc. Pharmacol., 32 (Suppl.3). S2-S13. Scholar google search Sakurai Т., Yanagasawa M., Takuwa Y., et al. (1990) Nature, 348, 732-735. Scholar google search Masaki N., Vane J.R., Vanhoutte P.M. (1994) Pharmacol. Rev., 46(2), 137-42. Scholar google search Russell F.D., Skepper J.N., Davenport A.P. (1997) J. Cardiovasc. Pharmacol., 29(6), 820-826. Scholar google search Russell F.D., Skepper J.N., Davenport A.P. (1998) J. Cardiovasc. Pharmacol., 31(3), 424-430. Scholar google search Dashwood M.R., Timm M., Muddle J.R. et al. (1998) Endothelium /New York, 6(1), 61-70. Scholar google search Douglas S.A., Ohlstein E.H. (1997) J. Vase. Res., 34(3), 152-164. Scholar google search Ruizopazo N., Hirayama K., Akimoto K. et al. (1998) Mol. Med., 4(2), 96-108. Scholar google search Ikeda U., Yamamoto K., Maeda Y. et al. (1997) Hypertension, 29(1 Part 1), 65-69. Scholar google search Shichiri M., Sedivy J.M., Marumo F., Hirata Y. (1998) Mol. Endocrin., 12(2), 172-180. Scholar google search Marsen T.A., Simonson M.S., Dunn M.J. (1995) Circ. Res., 76(6), 987-995. Scholar google search Golden C.L., Nick H.S., Visner G.A. (1998) Amer. J. Physiol.,18(5), L854-L863. Scholar google search Murata S., Matsumura Y., Takada K., Asai Y. et al. (1995) J. Pharmacol. Exp. Ther., 274(3), 1524-1530. Scholar google search Catalan R.E., Martinez A.M., Gargiulo L., LirasA. (1995) Biochem. Biophys. Res. Commun., 215(1), 219-226. Scholar google search Halim A., Kanayama N., Elmaradny E., Maehara K. el al. (1995) Thromb. Res., 80(2), 105-112. Scholar google search Zhang W.J., Bammer Т., Binder B.R., Wojta J. (1997) Fibrinolysis Proteolysis, 11(5-6), 245-250. Scholar google search Kapiotis S., Jilma В., Szalav T. et al. (1997) Arterioscler. Thromb. Vase. Biol, 17(11), 2861-2867. Scholar google search Ruschitzka F. Т., Noll G., Luscher T.F. (1997) Cardiology, 88 (Suppl.3), 3-19. Scholar google search Tiefenbacher СР., Chilian W.M. (1998) Basic. Res. Cardiol., 93(6), 446-454. Scholar google search Sharif L, Капе К.А., Wainwright C.L. (1998) Cardiovasc. Res., 39(3), 625-632. Scholar google search Alexiou K, Dschietzig Т., Simsch O, et al. (1998) J. Am. Coll. Cardiol., 32(6), 1773-1778. Scholar google search Bohnemeier H., Pinto Y.M., Horkay F., Toth M. et al. (1998) Clin. Exper. Hypertens., 20(4), 417-437. Scholar google search Maguire J.J., Davenport A.P. (1998) Br.J.Pharmacol., 125(2), 238-240. Scholar google search Minamino L, Kurihara K, Takahashi M. et al. (1997) Circulation, 95(1), 221-230. Scholar google search Sharma P., Lu F., Rut A., Brown M.J. (1998) Biochem. Biophys. Res. Commun., 245(3), 709-712. Scholar google search Kaburagi S., Hasegawa K, Morimoto Т., Araki M. et al. (1999) Circulation, 99(2), 292-298. Scholar google search Monge J.C. (1998) J. Cardiovasc. Pharmacol., 32(Suppl.2), S36-S42. Scholar google search Omland Т., Lie R. Т., Aarsland Т., Dickstein К (1994) Circulation, 89,1573-1579. Scholar google search Haug C, Koenig W., Hoeher M. Kochs M. et al. (1998) Clin. Chem. 44(2), 239-243. Scholar google search Oie E., Vinge L.E., Tonnessen Т., Grogaard H.K. et al. (1997) Amer. J. Physiol. Heart Circ. Phys., 42(4), H1727-H1736. Scholar google search Gray M.O., Long C.S., Kalinyak J.E., LiH.T., Karliner J.S. (1998) Cardiovasc. Res', 40(2), 352-363. Scholar google search Kiowski W., Sutsch G., Hunziker P.et al. (1995) Lancet, 346(8977), 732-736. Scholar google search Mulder P., Richard V., Derumeaux G., Hogie M. et al. (1997) Circulation, 96(6), 1976-1982. Scholar google search Ohnishi M., Wada A., Tsutarnoto Т., Fukai D. et al. (1998) Cardiovasc Res. 39(3), 617-624. Scholar google search Sutsch G., Kiowski W., Yan X. W., Hunziker P. et al. (1998) Circulation, 98(21), 2262-2268. Scholar google search Spinarova L., Toman J., Pospisilova J., Soucek M. et al. (1998) Int. J. Cardiol., 65(3), 227-232. Scholar google search Moreau P. (1998) Review Cardiovasc. Res., 39(3), 534-542. Scholar google search Pintosietsma S.J., Paul M. (1998) Kidney Int., 54(Suppl.67), S115-S121. Scholar google search Iyer R.S., Singh G., Rebello S. et al. (1995) Pharmacology, 1(2), 96-104. Scholar google search Dai S.M., Shan Z.Z., Miao С Y., Yin M., Su D.F. (1997) J.Cardiovasc. Pharmacol, 30(4), 475-480. Scholar google search Ferri C, Bellini C, Desideri G. et al. (1997) Clin. Sci., 93(1), 35-41. Scholar google search Kirk A.D., Jacobson L.M., Heisey D.M., Fass N.A. et al. (1997) Transplantation, 64(12), 1716-1720. Scholar google search Disashi Т., Nonoguchi К. Iwaoka T. et al. (1997) Hypertension, 30(6), 1591-1597. Scholar google search Cacoub P., Dorent R., NatafP., Carayon A. et al. (1997) Cardiovasc Res, 33(1), 196-200. Scholar google search Giaid A. (1998) Chest, 114(3 Suppl), S208-S212. Scholar google search Willette R.N., Ohlstein E.H., Mitchell M.P, et al. (1997) J. Pharm. Exp. Ther., 280(2), 695-701. Scholar google search Prie S., Stewart DJ., Dupuis J. (1998) Circulation, 97(8), 744-751. Scholar google search Unoki H., Fan J.L., Watanabe T. (1999) Cell. Tissue Res., 295(1), 89-99. Scholar google search Maguire J.J., Johnson СМ., Mockridge J. W., Davenport A.P. (1997) Br. J. Pharmacol., 122(8), 1647-1654. Scholar google search Matsuura A., Kawashima S., Yamochi W. et al. (1997) Biochem. Biophys. Res. Coramun., 235(3), 713-716. Scholar google search Zimmermann M., Seifert V. (1998) Neurosurgery, 43(4), 863-875. Scholar google search Josko J., Hendryk S., Jedrzejowskaszypula H., Gwozdz B. et al. (1998) J. Physiol. Pharmacol., 49(3), 367-375. Scholar google search Wanebo J.E., Arthur A.S., Louis H.G., West K. et al. (1998) Neurosurgery, 43(6), 1409-1417. Scholar google search Sato M., Noble L.J. (1998)£rain Res., 809(1), 39-49. Scholar google search Touzani O., Galbraith S., Siegl P., Mcculloch J. (1997) J. Cereb. Blood Flow Metab., 17(11), 1157-1165. Scholar google search Sharma A.C., Misra M., Prat R., Alden K. et al. (1998) Neurol. Res., 20(7), 632-636. Scholar google search Gorlach C, Siren A.L., Knerlich F., Feger G. et al. (1998) J. Cerebr. Blood Flow Metabol., 18(12), 1357-1364. Scholar google search Zuccarello M., BoccalettiR., Rapoport R.M. (1998) Eur. J. Pharmacol., 357(1), 67-71. Scholar google search Caner H., Kwan A., Arthur A., JengA. et al. (1996) J. Neurosurg., 85, 917-722. Scholar google search Gorlach C, Benyo Z, Wahl M. (1998) Kidney Int., 54(Suppl.67), S224-S225. Scholar google search Lampl Y., Fleminger G., Gilad R. et al. (1997) Stroke, 28(10), 1951-1955. Scholar google search Benigni A., Remuzzi G. (1999) Lancet, 353(9147), 133-138. Scholar google search Schiffrin E.L. (1998) J. Hypertension, 16(12Part 2), 1891-1895. Scholar google search Wenzel R.R., Fleisch M., Shaw S. et al. (1998) Circulation, 98(21), 2235-2240. Scholar google search Jeng A.Y. (1997) Expert. Opin. Ther. Patents, 7(11), 1283-1295. Scholar google search De Lombaert S., Ghai R., Jeng A., Trapani A. and Webb R. (1994) Biochem. Biophys. Res. Commun., 204, 407-412. Scholar google search Rubanyi G.M., Polokoff M.A. (1994) Pharmacol. Reviews, 46(3), 325-415. Scholar google search