VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Aminopeptidases in human leukemic lymphoid cells

   
Gureeva T.A., Golubeva N.V., Lubkova O.N.
PubMed Id: 10547880
Year: 1999  Volume: 45  Issue: 4  Pages: 309-313
Aminopeptidase activity in lymphoid cells of patients with various lymphoproliferative diseases was studied. The enzyme activity was detected in lysates of all leukemic B- and T-cells. The lymphoid cells contained aminopeptidases of at least two classes: metallo- and SH-dependent enzymes. The SH-dependent aminopeptidase with pH optimum 8.5-9.0 was revealed in lymphoid cells for the first time, and it seems to belong to a poorly studied aminopeptidase family.
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Gureeva T.A., Golubeva N.V., Lubkova O.N. (1999) Voprosy meditsinskoi khimii, 45(4), 309-313.
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