VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The functional status of glutamate receptors by ethanol treatment

   
Golovko S.I., Zefirov S.J., Golovko A.I., Schpilenja L.S., Nekracov J.A., Romanenko O.I.
PubMed Id: 10635530
Year: 1999  Volume: 45  Issue: 5  Pages: 368-374
A growing bulk of experimental data indicates that change of certain neurotransmitter receptors and voltage-dependent ion cannels are characteristic manifestations accompanying ethanol consumption. A likely target for ethanol effects is the glutamate receptors. Glutamate is one of major excitatory neurotransmitter in the mammalian brain. While the acute application of ethanol inhibits glutamate-induced cationic currents, chronic treatment with ethanol leads to an up-regulation of glutamate receptors.
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Keywords: ethanol, glutamate, receptors
Citation:

Golovko, S. I., Zefirov, S. J., Golovko, A. I., Schpilenja, L. S., Nekracov, J. A., Romanenko, O. I. (1999). The functional status of glutamate receptors by ethanol treatment. Voprosy Meditsinskoi Khimii, 45(5), 368-374.
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