VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Common properties of pharmacological agonists and antagonists of external membrane receptors

   
Luik A.I., Prokopenko V.V., Tanchuk V.Yu., Kholodovich V.V., Semenuta I.V.
PubMed Id: 10761218
Year: 1999  Volume: 45  Issue: 6  Pages: 514-524
Using experimental transcription model in vitro, and method of electron-topological calculations the elements of pharmacological and structural community have been found in the groups of physiologically active compounds (PAC), blocking and activating external cellular receptors. This finding confirms the necessity of subdivision special groups of bio-substrates blockators and activators for hierarchical classification, of PAC.
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Luik, A. I., Prokopenko, V. V., Tanchuk, V. Yu., Kholodovich, V. V., Semenuta, I. V. (1999). Common properties of pharmacological agonists and antagonists of external membrane receptors. Voprosy Meditsinskoi Khimii, 45(6), 514-524.
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