VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The use of ionselective field transistors (isfets) with photocurable polyurethane membranes innephrology for determination of k+ concentration (activity)

   
Abramova N. Yu., Borisov Yu.A., Bratov A. V., Gavrilenkov P. V., Domingue K. Z., Spiridonov V.N., Suglobova E.D.
PubMed Id: 10761220
Year: 1999  Volume: 45  Issue: 6  Pages: 530-537
The applicability is examined of ion selective field transistors with photocurable polyurethane membranes to control of the electrolytic composition of dialyzing solutions used in artificial kidney apparatus, and also of plasma in patient treated by chronic hemodialysis. The short- and long-time characteristics of the efficiency of K(+)-selective field transistors in continuous contact with solutions. Comparative testing of such transistors and other sensing systems is made. It is demonstrated that a sufficient reliability of measurements in the range of physiological concentrations in combination with low cost provide the possibility of using K(+)-selective field transistors for monitoring of the potassium concentration both in dialyzing solutions and plasma in patients on chronic hemodialysis treatment.
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Abramova N. Yu., Borisov Yu.A., Bratov A. V., Gavrilenkov P. V., Domingue K. Z., Spiridonov V.N., Suglobova E.D. (1999) Voprosy meditsinskoi khimii, 45(6), 530-537.
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