VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The study of metabolic changes in rat liver during a reductive period after overheating

   
INzhevatkin E.V.1, Savchenko A.A.1, Albrant A.I.1, Nefedov V.P.2

1. Krasnoyarsk State University
2. International Scientific Centre for Organism Extreme Conditions research (ISCOECR) at Presidium of Krasnoyarsk Scientific centre
PubMed Id: 10885033
Year: 2000  Volume: 46  Issue: 2  Pages: 135-139
The metabolic changes in rat liver were studied during a reduction period after the overheating (25 min, 42° C) using the isolated organ perfusion. First six hours after the treatment were characterised by a decrease of the respiration rate, the activation of glycolysis and an exhaustion of hepatic carbohydrate resources. The development of adaptive reaction resulted in the recovery of respiration rate to 18 h. This may provide subsequent restoration of hepatic metabolism and normalisation of the organ functioning
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INzhevatkin E.V., Savchenko A.A., Albrant A.I., Nefedov V.P. (2000) Voprosy meditsinskoi khimii, 46(2), 135-139.
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