VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The influence of thyroxine on the enzymes of energy metabolism in bone marrow myeloid cells and neutrophilsof neonatal piglet

   
Babych N.O.1, Antonyak H.L.2, Tymochko M.F.1

1. Lviv State Medical University
2. Institute of Agriculture and Animal Biology
PubMed Id: 10885037
Year: 2000  Volume: 46  Issue: 2  Pages: 162-167
The influence of thyroxine on the activities of enzymes of energy metabolism (hexokinase, 6-phosphofructokinase, pyruvate kinase, lactate dehydrogenase, glucose-6-phosphate dehydrogenase, NADP-isocitrate dehydrogenase, cytochrome c oxidase) was investigated in bone marrow myeloid cells and blood neutrophils of 3-10-day old neonatal piglets. Data obtained suggest different responsiveness of energy metabolism enzymes to thyroxine action. Repeated hormone injections resulted in the preferential stimulation of enzymes involved in oxidative stages of carbohydrate catabolism in animal myelocaryocytes, while the activities of anaerobic enzymes in these cells were less affected. At the same time glycolytic enzymes in neutrophil granulocytes showed higher sensitivity to thyroxine action than enzymes catalyzing oxidative stages of energy metabolism.
Download PDF:
Reference:

Babych N.O., Antonyak H.L., Tymochko M.F. (2000) Voprosy meditsinskoi khimii, 46(2), 162-167.
References  
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
        

© Institute of Biomedical Chemistry, Moscow, Russia