VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The effect ofantibiotic therapy on embryotropic antibodies in women

   
Morozov S.G.1, Poletaev A.B.2, Radzinsky V.E.3, Protsenko A.N.3, Korgenevskii D.A.4

1. Municipal hospital №29 Committee for health, Moscow, Orekhovich Institute of Biomedical Chemistry RAMS
2. Fund Chernobyl-Test
3. Department of obstetrics and gynecology, Peoples Frendship University, Moscow
4. Orekhovich Institute of Biomedical Chemistry RAMS
PubMed Id: 11450447
Year: 2001  Volume: 47  Issue: 2  Pages: 256-154
Embriotropic antibodies (e-Ab) serum contents were analysed in 29 serum samples obtained from women suffering with primary lues. Before treatment the content of e-Ab against MBP, S100, ACBP14/18, and MP65 were markedly elevated in 28 samples. Two injections of Retarpen (2.5 mln Units with one week interval) were enough for effective treatment of lues. At the same time treatment caused deep and reversible inhibition of e-Ab production. One or two months later the levels of e-Ab returned to normal values in 21% of women, in 52% patients the hypoproduction, and in 27% the hyperproduction of e-Ab were noted. Deviations of e-Ab production after effective retarpen treatment suggest the existence of additional reasons which may influence e-Ab production, and necessity of additional diagnostic and curative measures for such women during pregravidal period.
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Morozov, S. G., Poletaev, A. B., Radzinsky, V. E., Protsenko, A. N., Korgenevskii, D. A. (2001). The effect ofantibiotic therapy on embryotropic antibodies in women. Voprosy meditsinskoi khimii, 47(2), 256-154.
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