The effect of intravenous administration of lactate dehydrogenase (5000 E/kg) on some metabolic parameters was investigated. The hyperenzymemia was accompanied by changes of metabolite content (glutamate, 2-oxoglutarate, lactate, dihydroxyacetone phosphate) and enzyme activities (aldolase, lactate dehydrogenase, transaminase) in heart, liver and skeletal muscles. Intravenously administered tritiated lactate dehydrogenase was preferentially found in skeletal muscles, liver, kidneys and some other organs.
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Gilmiyarova F.N., Radomskaya V.M., Kretova I.G., Kleiman M.S., Pervova Yu.V. (2001) Role of hyper lactate dehydrogenazemia in induction of metabolic disturbance inorganism. Voprosy Meditsinskoi Khimii, 47(5), 469-476.
Gilmiyarova F.N. et al. Role of hyper lactate dehydrogenazemia in induction of metabolic disturbance inorganism // Voprosy Meditsinskoi Khimii. - 2001. - V. 47. -N 5. - P. 469-476.
Gilmiyarova F.N. et al., "Role of hyper lactate dehydrogenazemia in induction of metabolic disturbance inorganism." Voprosy Meditsinskoi Khimii 47.5 (2001): 469-476.
Gilmiyarova, F. N., Radomskaya, V. M., Kretova, I. G., Kleiman, M. S., Pervova, Yu. V. (2001). Role of hyper lactate dehydrogenazemia in induction of metabolic disturbance inorganism. Voprosy Meditsinskoi Khimii, 47(5), 469-476.
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