VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Role of hyper lactate dehydrogenazemia in induction of metabolic disturbance inorganism

   
Gilmiyarova F.N.1, Radomskaya V.M.1, Kretova I.G.1, Kleiman M.S.1, Pervova Yu.V.1

1. Department of Fundamental and Clinical Biochemistry with Laboratory Diagnostic of Samara State Medical University
PubMed Id: 11766256
Year: 2001  Volume: 47  Issue: 5  Pages: 469-476
The effect of intravenous administration of lactate dehydrogenase (5000 E/kg) on some metabolic parameters was investigated. The hyperenzymemia was accompanied by changes of metabolite content (glutamate, 2-oxoglutarate, lactate, dihydroxyacetone phosphate) and enzyme activities (aldolase, lactate dehydrogenase, transaminase) in heart, liver and skeletal muscles. Intravenously administered tritiated lactate dehydrogenase was preferentially found in skeletal muscles, liver, kidneys and some other organs.
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Gilmiyarova, F. N., Radomskaya, V. M., Kretova, I. G., Kleiman, M. S., Pervova, Yu. V. (2001). Role of hyper lactate dehydrogenazemia in induction of metabolic disturbance inorganism. Voprosy meditsinskoi khimii, 47(5), 469-476.
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