VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Regulation of serum ceruloplasmin activity in women with gynecological tumors

   
Goussarova Yu.N.1, Stepanova E. V.2, Landesman E.O.2, Koroleva O.V.2, Vavilova T.P.1, Makarov O.V.3, Kosetsky V.N.3

1. Moscow State Stomatological University
2. Bakh Institute of Biochemistry, Russian Academy of Sciences
3. Russian State Medical University
PubMed Id: 12506616
Year: 2002  Volume: 48  Issue: 4  Pages: 388-393
Serum ceruloplasmih (CP) and anti-CP antibody levels were studied by the oxidase method in 18 healthy women and in 86 women with gynecological tumors. The results demonstrate that: 1) Serum CP concentrations increased in endometrial and ovarian cancer, in benign ovarian tumors and to a lesser extent in mioma of uterus. 2) Serum CP antibodies were found out in both benign tumors and cancer cases. 3) There was positive linear correlation between serum levels of CP and anti-CP-antibodies in endometrial and ovarian cancers, and in benign ovarian tumors.
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Goussarova Yu.N., Stepanova E. V., Landesman E.O., Koroleva O.V., Vavilova T.P., Makarov O.V., Kosetsky V.N. (2002) Voprosy meditsinskoi khimii, 48(4), 388-393.
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