he effect of UV radiation in vitro on the level of ascorbate, SH-groups and glutathione reductase activity in the soluble fraction of bovine eye lens was studied. UV-Irradiation increased NADPH-oxidoreductase activity, the level of ascorbate oxidation and decreased the content of SH-groups and activity of glutathione reductase. Significant activation of the NADPH-oxidoreductase activity in the presence of ascorbate and Cu2+ was observed after UV-irradiation. It is suggested thаt ascorbate may play an important role in the UV-induced lens pathology
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Byshneva L.N., Senchuk V.V. (2002) Effect of UV-radiation on the level of ascorbate, SH-groups and activity of glutathione reductase in the eyelens. Voprosy Meditsinskoi Khimii, 48(5), 455-460.
Byshneva L.N. et al. Effect of UV-radiation on the level of ascorbate, SH-groups and activity of glutathione reductase in the eyelens // Voprosy Meditsinskoi Khimii. - 2002. - V. 48. -N 5. - P. 455-460.
Byshneva L.N. et al., "Effect of UV-radiation on the level of ascorbate, SH-groups and activity of glutathione reductase in the eyelens." Voprosy Meditsinskoi Khimii 48.5 (2002): 455-460.
Byshneva, L. N., Senchuk, V. V. (2002). Effect of UV-radiation on the level of ascorbate, SH-groups and activity of glutathione reductase in the eyelens. Voprosy Meditsinskoi Khimii, 48(5), 455-460.
References
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