VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Changes in system of antioxidant blood defence in newborns with different pathology

   
Litvinenco L.A.1, Danilova L.A.1, Shabalov  N.P.1

1. Saint-Petersburg Pediatric Medical Academy
PubMed Id: 12498095
Year: 2002  Volume: 48  Issue: 5  Pages: 513-518
Blood antioxidant enzymes (superoxide dismutase, catalase, ceruloplasmin) were investigated in gestational ages and diseases. Low activity of blood superoxide dismutase and catalase were observed in premature babies and in newborns after acute and chronic hypoxia. In hemolytic disease the aсtivity of antioxidant enzymes of newborns was significantly higher than in healthy infants. This work demonstrates advantages of haemosorbtion compared to exchange blood transfusion. So the antioxidant activity in blood, decreased after blood transfusion, remained at a high level after haemosorbtion. Аny deficiency of antioxidant enzymes in newborns may lead to toxyc oxygen effects. Antioxidants are potential therapeutic agents in the above mentioned conditions
Download PDF:
Citation:

Litvinenco, L. A., Danilova, L. A., Shabalov, , N. P. (2002). Changes in system of antioxidant blood defence in newborns with different pathology. Voprosy meditsinskoi khimii, 48(5), 513-518.
References  
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
 1986 (vol 32)
 1985 (vol 31)