VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Serum anti-S100, anti-GFAP and anti-MP65 autoantibodies inpregnants with early toxicosis

   
Morozov S.G., Poletaev A.B., Murashko L.Е., Dyakova E.P., Ponomareva I.V., Gnedenko B.B., Sukhikh G.T.
PubMed Id: 10599145
Year: 1998  Volume: 44  Issue: 6  Pages: 576-583
Serum levels/affinities of natural autoantibodies to proteins S100, GFAP and MP65 in patients with physiological pregnancy are usually constant and may vary among individuals within relatively narrow range. In patients with early toxicosis in pregnancy dispersion of serum autoantibodies levels were often found beyond the normal range. This group includes cases with significantly elevated as well as abnormally decreased immunoreactivity parameters. Percent of newborns with different deviations from women with abnormal serum levels/affinities of autoantibodies to proteins S100, GFAP and MP65 was higher 1,5-2 fold compared with population.
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Morozov S.G., Poletaev A.B., Murashko L.Е., Dyakova E.P., Ponomareva I.V., Gnedenko B.B., Sukhikh G.T. (1998) Voprosy meditsinskoi khimii, 44(6), 576-583.
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