VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Carbohydrate metabolism during poisoning with the cholinesterase inhibitor O-ethyl-S-hexylmethylthiophosphonate

   
Rozengart V.I., Chetverikova E.K., Mozgovaia I.A.
PubMed Id: 5317625
Year: 1971  Volume: 17  Issue: 4  Pages: 403-407
It is established that a decrease in glycogen content in liver begins at the early stages of intoxication with LG-63 and progresses with development of intoxication phenomena. Sugar content in liver and blood augments in parallel with decreasing content of glycogen in liver; concentration of ketone bodies and content of bisulfite-binding substances and pyruvic acid in liver also increase. In skeletal muscles, glycogen content was practically without changes; content of sugar, bisulfite-binding substances and pyruvic acid decreased while level of ketone bodies increased. In brain, utilization of ketone bodies decreased and in myocardium, increased.
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Rozengart, V. I., Chetverikova, E. K., Mozgovaia, I. A. (1971). Carbohydrate metabolism during poisoning with the cholinesterase inhibitor O-ethyl-S-hexylmethylthiophosphonate. Voprosy Meditsinskoi Khimii, 17(4), 403-407.
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