VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Features of RNA synthesis in isolated cell nuclei of M-1 sarcoma and rat liver

   
Rubtsova G.V., Botrin I.I., Debov S.S.
PubMed Id: 5317628
Year: 1971  Volume: 17  Issue: 4  Pages: 415-422
As evidenced from investigation of patterns of RNA synthesis in cell nuclei of sarcoma M-1 and rat liver, RNA-polymerase activity depends on the presence of ribonucleoside triphosphates in the incubation medium. Inhibition of polymerase reaction was noted in the presence of DNAase, RNAase and actinomycin D. An increase in ionic strength of incubation medium induced a sharp increase in C14-UMP incorporation into RNA by cell nuclei of sarcoma M-1 and normal liver compared to regenerating liver and was followed by changes in nucleotide pattern of formed RNA with prevalence of AU-type As evidenced from investigation of products of RNA-polymerase reaction in sucrose density gradient, RNA synthesized by cell nuclei of sarcoma M-1 is represented by a low molecular weight fraction.
Download PDF:  
Citation:

Rubtsova, G. V., Botrin, I. I., Debov, S. S. (1971). Features of RNA synthesis in isolated cell nuclei of M-1 sarcoma and rat liver. Voprosy Meditsinskoi Khimii, 17(4), 415-422.
References
 1984 (vol 30)
 1983 (vol 29)
 1982 (vol 28)
 1981 (vol 27)
 1980 (vol 26)
 1979 (vol 25)
 1978 (vol 24)
 1977 (vol 23)
 1976 (vol 22)
 1975 (vol 21)
 1974 (vol 20)
 1973 (vol 19)
 1972 (vol 18)
 1971 (vol 17)
 1970 (vol 16)
 1969 (vol 15)
 1968 (vol 14)
 1967 (vol 13)
 1966 (vol 12)
 1965 (vol 11)
◄        ►