Effect of acute overheating of animals on the processes of lipid peroxidation

Shepelev A.P.
PubMed Id: 829005
Year: 1976  Volume: 22  Issue: 1  Pages: 47-51
In liver tissue, brain, lungs and skeletal muscles of rats, subjected to overheating, content of conjugated diens and lipid peroxides was distinctly increased. The decrease in the period of malon dialdehyde induction and in the antioxidative activity of lipids correlated with the alteration in content of peroxidation products. The overheating of animals was accompanied by a decrease in unsaturation of lipids in liver tissue, brain and skeletal muscles due to a decrease in amounts of arachidonic acid and to an increase in content of palmitinic and stearinic acids. In lipids of lungs the unsaturation was increased as a result of increase in content of linoleic acid. Administration of alpha-tocopherol and ionol, 10 min before the overheating and in hypothermia, exhibited a protective effect, thioTEPA caused an opposite action. Administration of alpha-tocopherol and ionol 24 hrs before the thermic treatment decreased the survival period of the animals which were subjected to the overheating.
Download PDF:  

Shepelev, A. P. (1976). Effect of acute overheating of animals on the processes of lipid peroxidation. Voprosy Meditsinskoi Khimii, 22(1), 47-51.
 1984 (vol 30)
 1983 (vol 29)
 1982 (vol 28)
 1981 (vol 27)
 1980 (vol 26)
 1979 (vol 25)
 1978 (vol 24)
 1977 (vol 23)
 1976 (vol 22)
 1975 (vol 21)
 1974 (vol 20)
 1973 (vol 19)
 1972 (vol 18)
 1971 (vol 17)
 1970 (vol 16)
 1969 (vol 15)
 1968 (vol 14)
 1967 (vol 13)
 1966 (vol 12)
 1965 (vol 11)