VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Tissue metabolism of thyroid hormones in cirrhosis of the liver

   
Mirakhmedov M.M., Turakulov I.Kh.
PubMed Id: 1014477
Year: 1976  Volume: 22  Issue: 5  Pages: 655-659
Content and ratio of products of iodothyronine tissue metabolism was studied in liver tissue of rats in normal state and in hepatocirrhosis after administration of 125I-thyroxin. The distinct decrease was observed in accumulation, deiodination and conjugation of thyroxin; the hormone was also converted into triiodothyronine in cirrhotically altered liver tissue. The importance of liver tissue in maintenance of hormonal homeostasis and biological activation of thyroid hormones is discussed.
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Mirakhmedov, M. M., Turakulov, I. Kh. (1976). Tissue metabolism of thyroid hormones in cirrhosis of the liver. Voprosy Meditsinskoi Khimii, 22(5), 655-659.
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