VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Binding of C14-histamine by plasma membranes of cells from gastric mucosa of rats

   
Bersimbaev R.I.
PubMed Id: 1027247
Year: 1976  Volume: 22  Issue: 6  Pages: 728-732
It was established that in rat gastric mucosa cells the receptor proteins capable of binding 14C-histamine were components of plasma membranes. Analysis (by Scatchard method) of curves of 14C-histamine binding by receptor proteins demonstrated that in plasma membranes there were two types of receptors: with high and low affinity to histamine. A specific histamine H2-receptor blockator--burimamide--inhibited competitively the binding of labelled histamine by plasma membranes. The data obtained suggest that the activation of adenyl cyclase by histamine is the result of specific binding of this amine by proteins of plasma membranes in rat gastric mucosa cells.
Download PDF:  
Citation:

Bersimbaev, R. I. (1976). Binding of C14-histamine by plasma membranes of cells from gastric mucosa of rats. Voprosy Meditsinskoi Khimii, 22(6), 728-732.
References
 1984 (vol 30)
 1983 (vol 29)
 1982 (vol 28)
 1981 (vol 27)
 1980 (vol 26)
 1979 (vol 25)
 1978 (vol 24)
 1977 (vol 23)
 1976 (vol 22)
 1975 (vol 21)
 1974 (vol 20)
 1973 (vol 19)
 1972 (vol 18)
 1971 (vol 17)
 1970 (vol 16)
 1969 (vol 15)
 1968 (vol 14)
 1967 (vol 13)
 1966 (vol 12)
 1965 (vol 11)
◄        ►